PYHIN1
pyrin and HIN domain family, member 1
Synonyms:
IFIX, RP11-520H16.1
Species:
UniProtKB ID:
Gene ID:
- Human(149628) Summary: The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- Mouse(236312) pyrin and HIN domain family, member 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PYHIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Proteins
Product Number
Description
Species
PrEST Antigen PYHIN1, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human