PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
Synonyms:
BDP1, PTP-HSCF
Species:
Human PTPN18 (26469), Mouse Ptpn18 (19253), Rat Ptpn18 (301333), Horse PTPN18 (100067347), Domestic Rabbit PTPN18 (100346705), cow PTPN18 (617215), sheep PTPN18 (101116547), Zebrafish ptpn18 (541324), cow PTPN18 (282334), domestic cat PTPN18 (101091072) ...More
UniProtKB ID:
Gene ID:
- Human(26469) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
- Mouse(19253) protein tyrosine phosphatase, non-receptor type 18
- Rat(301333) protein tyrosine phosphatase, non-receptor type 18
- Horse(100067347) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- Domestic Rabbit(100346705) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- cow(617215) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- sheep(101116547) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- Zebrafish(541324) protein tyrosine phosphatase, non-receptor type 18
- cow(282334) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- domestic cat(101091072) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- naked mole-rat(101706897) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- domestic guinea pig(100722394) protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
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