PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
Synonyms:
HC10-II
Species:
Human PSMB3 (5691), Mouse Psmb3 (26446), Rat Psmb3 (29676), chicken PSMB3 (419997), sheep PSMB3 (101120589), cow PSMB3 (533874), dog PSMB3 (480537), Zebrafish psmb3 (573095), naked mole-rat Psmb3 (101720602), domestic cat PSMB3 (101087282)
UniProtKB ID:
Gene ID:
- Human(5691) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12. [provided by RefSeq, Jul 2008]
- Mouse(26446) proteasome (prosome, macropain) subunit, beta type 3
- Rat(29676) proteasome (prosome, macropain) subunit, beta type 3
- chicken(419997) proteasome (prosome, macropain) subunit, beta type, 3
- sheep(101120589) proteasome (prosome, macropain) subunit, beta type, 3
- cow(533874) proteasome (prosome, macropain) subunit, beta type, 3
- dog(480537) proteasome (prosome, macropain) subunit, beta type, 3
- Zebrafish(573095) proteasome (prosome, macropain) subunit, beta type, 3
- naked mole-rat(101720602) proteasome (prosome, macropain) subunit, beta type, 3
- domestic cat(101087282) proteasome (prosome, macropain) subunit, beta type, 3
- domestic guinea pig(100719768) proteasome (prosome, macropain) subunit, beta type, 3
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