PRKCE
protein kinase C, epsilon
Synonyms:
PKCE, nPKC-epsilon
Species:
Human PRKCE (5581), Mouse Prkce (18754), Rat Prkce (29340), chicken PRKCE (421409), domestic cat PRKCE (101100958), dog PRKCE (609934), cow PRKCE (507041), Horse PRKCE (100053394), Domestic Rabbit PRKCE (100009103), sheep PRKCE (101110314) ...More
UniProtKB ID:
Gene ID:
- Human(5581) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
- Mouse(18754) protein kinase C, epsilon
- Rat(29340) protein kinase C, epsilon
- chicken(421409) protein kinase C, epsilon
- domestic cat(101100958) protein kinase C, epsilon
- dog(609934) protein kinase C, epsilon
- cow(507041) protein kinase C, epsilon
- Horse(100053394) protein kinase C, epsilon
- Domestic Rabbit(100009103) protein kinase C, epsilon
- sheep(101110314) protein kinase C, epsilon
- naked mole-rat(101700837) protein kinase C, epsilon
- domestic guinea pig(100721814) protein kinase C, epsilon
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Small Molecule - Agonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PKC ε antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-PKCε (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PKCε Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PKCε Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant PKCε, amino acids 2-end. For use in Kinase Assays.,
Species
human
PrEST Antigen PRKCE, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PKC ε , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human