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Merck

PKD2

polycystic kidney disease 2 (autosomal dominant)

Synonyms:
APKD2, PC2, PKD4, Pc-2, TRPP2
Species:
UniProtKB ID:
Gene ID:
  • Human(5311) Summary: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
  • Mouse(18764) polycystic kidney disease 2
  • Rat(498328) polycystic kidney disease 2 (autosomal dominant)
  • chicken(422585) polycystic kidney disease 2 (autosomal dominant)
  • Zebrafish(432387) polycystic kidney disease 2
  • dog(487852) polycystic kidney disease 2 (autosomal dominant)
  • Domestic Rabbit(100008872) polycystic kidney disease 2 (autosomal dominant)
  • sheep(101103569) polycystic kidney disease 2 (autosomal dominant)
  • naked mole-rat(101726639) polycystic kidney disease 2 (autosomal dominant)
  • domestic cat(101098948) polycystic kidney disease 2 (autosomal dominant)
  • domestic guinea pig(100714947) polycystic kidney disease 2 (autosomal dominant)
  • fruit fly(34651) Polycystic kidney disease gene-2
  • cow(530393) polycystic kidney disease 2 (autosomal dominant)

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Polycystin-L Antibody, serum, Chemicon®,
Species Reactivity
mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-PKD2 antibody produced in mouse, clone 4C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-PKD2 Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-Polycystin-2 Antibody, serum, Chemicon®,
Species Reactivity
mouse
Application
immunocytochemistry
immunohistochemistry

western blot