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Merck

PIP4K2A

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

Synonyms:
PI5P4KA, PIP5K2A, PIP5KII-alpha, PIP5KIIA, PIPK
Species:
UniProtKB ID:
Gene ID:
  • Human(5305) Summary: Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq, Jul 2008]
  • Mouse(18718) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • Rat(116723) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • Domestic Rabbit(100340683) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • naked mole-rat(101705091) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • sheep(101103999) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • cow(533289) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • domestic guinea pig(100718003) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • Horse(100066733) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • domestic cat(101096576) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • dog(608414) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • chicken(420504) phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

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