PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
Synonyms:
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Species:
Human PDGFRA (5156), Mouse Pdgfra (18595), Rat Pdgfra (25267), chicken PDGFRA (395509), domestic guinea pig Pdgfra (100726209), cow PDGFRA (282301), Zebrafish pdgfra (386856), domestic cat PDGFRA (101090765), sheep PDGFRA (101106012), dog PDGFRA (442860) ...More
UniProtKB ID:
Gene ID:
- Human(5156) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
- Mouse(18595) platelet derived growth factor receptor, alpha polypeptide
- Rat(25267) platelet derived growth factor receptor, alpha polypeptide
- chicken(395509) platelet-derived growth factor receptor, alpha polypeptide
- domestic guinea pig(100726209) platelet-derived growth factor receptor, alpha polypeptide
- cow(282301) platelet-derived growth factor receptor, alpha polypeptide
- Zebrafish(386856) platelet derived growth factor receptor alpha
- domestic cat(101090765) platelet-derived growth factor receptor, alpha polypeptide
- sheep(101106012) platelet-derived growth factor receptor, alpha polypeptide
- dog(442860) platelet-derived growth factor receptor, alpha polypeptide
- Horse(100059815) platelet-derived growth factor receptor, alpha polypeptide
- naked mole-rat(101697360) platelet-derived growth factor receptor, alpha polypeptide
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD140a antibody produced in mouse, clone 16A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD140a-APC antibody produced in mouse, clone 16A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-PDGFR α antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Platelet-Derived Growth Factor Receptor α antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
human
Application
ELISA
immunohistochemistry
neutralization
western blot
immunohistochemistry
neutralization
western blot
Anti-PDGFRα Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-pyrrole-3-propanoic acid, ,
Species
human
Proteins
Product Number
Description
Species
Platelet-Derived Growth Factor-AA human, PDGF-AA, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
PDGFRα Protein, active, 50 µg, Active, recombinant human PDGFRα, residues 550-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Species
human
PDGFR-α (T674I), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human