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Merck

PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

Synonyms:
Hcam3
Species:
UniProtKB ID:
Gene ID:
  • Human(5137) Summary: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]
  • Mouse(18575) phosphodiesterase 1C
  • Rat(81742) phosphodiesterase 1C
  • domestic cat(101089682) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • fruit fly(34594) CG44007 gene product from transcript CG44007-RG
  • Zebrafish(100536162) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • chicken(420752) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • domestic guinea pig(100726194) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • dog(475272) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • sheep(101121508) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • Domestic Rabbit(100347155) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • Horse(100070015) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • cow(526211) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • naked mole-rat(101717015) phosphodiesterase 1C, calmodulin-dependent 70kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PDE1C antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Vinpocetine, ≥98%, solid,
Species
human
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Species
human
Dipyridamole, European Pharmacopoeia (EP) Reference Standard,
Species
human
Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Dipyridamole, ≥98% (HPLC),
Species
mouse, human

Proteins

Product Number
Description
Species
PDE1C, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human