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Merck

PABPC1

poly(A) binding protein, cytoplasmic 1

Synonyms:
PAB1, PABP, PABP1, PABPC2, PABPL1
Species:
Human PABPC1 (26986), Mouse Pabpc1 (18458), Rat Pabpc1 (171350), Horse PABPC1 (100056021), cow PABPC1 (282296), sheep PABPC1 (100135436), domestic guinea pig Pabpc1 (100727743), naked mole-rat Pabpc1 (101721124), chicken PABPC1 (430997), dog PABPC1 (612751)
UniProtKB ID:
P11940, Q15097, Q93004
Gene ID:
  • Human(26986) Summary: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]
  • Mouse(18458) poly(A) binding protein, cytoplasmic 1
  • Rat(171350) poly(A) binding protein, cytoplasmic 1
  • Horse(100056021) poly(A) binding protein, cytoplasmic 1
  • cow(282296) poly(A) binding protein, cytoplasmic 1
  • sheep(100135436) poly(A) binding protein, cytoplasmic 1
  • domestic guinea pig(100727743) poly(A) binding protein, cytoplasmic 1
  • naked mole-rat(101721124) poly(A) binding protein, cytoplasmic 1
  • chicken(430997) poly(A) binding protein, cytoplasmic 1
  • dog(612751) poly(A) binding protein, cytoplasmic 1
  • domestic cat(101083238) poly(A) binding protein, cytoplasmic 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2108698
Anti-PABPC1, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
HPA045423
Anti-PABPC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
P6246
Anti-PABP antibody, Mouse monoclonal, clone 10E10, purified from hybridoma cell culture,
Species Reactivity
xenopus, bovine, canine, hamster, human, monkey
Application
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
04-1467
Anti-PABP 1 Antibody, clone 10E10, clone 10E10, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot