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Merck

P4HA2

prolyl 4-hydroxylase, alpha polypeptide II

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(8974) Summary: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(18452) procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
  • Rat(360526) prolyl 4-hydroxylase, alpha polypeptide II
  • domestic guinea pig(100718564) prolyl 4-hydroxylase, alpha polypeptide II
  • naked mole-rat(101724121) prolyl 4-hydroxylase, alpha polypeptide II
  • Zebrafish(373132) procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
  • chicken(416326) prolyl 4-hydroxylase, alpha polypeptide II
  • dog(474672) prolyl 4-hydroxylase, alpha polypeptide II
  • domestic cat(101094394) prolyl 4-hydroxylase, alpha polypeptide II
  • cow(507327) prolyl 4-hydroxylase, alpha polypeptide II
  • Domestic Rabbit(100328721) prolyl 4-hydroxylase, alpha polypeptide II

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