OPHN1
oligophrenin 1
Synonyms:
ARHGAP41, MRX60, OPN1
Species:
Human OPHN1 (4983), Mouse Ophn1 (94190), Rat Ophn1 (312108), dog OPHN1 (607363), Zebrafish ophn1 (436982), chicken OPHN1 (422162), sheep OPHN1 (101120140), cow OPHN1 (101909620), domestic cat OPHN1 (101082045), domestic guinea pig Ophn1 (100379222)
UniProtKB ID:
Gene ID:
- Human(4983) Summary: This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism. [provided by RefSeq, Jul 2008]
- Mouse(94190) oligophrenin 1
- Rat(312108) oligophrenin 1
- dog(607363) oligophrenin 1
- Zebrafish(436982) oligophrenin 1
- chicken(422162) oligophrenin 1
- sheep(101120140) oligophrenin 1
- cow(101909620) oligophrenin 1
- domestic cat(101082045) oligophrenin 1
- domestic guinea pig(100379222) oligophrenin 1
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