NLRP10
NLR family, pyrin domain containing 10
Synonyms:
CLR11.1, NALP10, NOD8, PAN5, PYNOD
Species:
Human NLRP10 (338322), Mouse Nlrp10 (244202), Rat Nlrp10 (293426), dog NLRP10 (611323), Horse NLRP10 (100070865), domestic cat NLRP10 (101089644), naked mole-rat Nlrp10 (101702326)
UniProtKB ID:
Gene ID:
- Human(338322) Summary: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(244202) NLR family, pyrin domain containing 10
- Rat(293426) NLR family, pyrin domain containing 10
- dog(611323) NLR family, pyrin domain containing 10
- Horse(100070865) NLR family, pyrin domain containing 10
- domestic cat(101089644) NLR family, pyrin domain containing 10
- naked mole-rat(101702326) NLR family, pyrin domain containing 10
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