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Merck

NFKBIB

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

Synonyms:
IKBB, TRIP9
Species:
UniProtKB ID:
Gene ID:
  • Human(4793) Summary: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18036) nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
  • Rat(81525) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • dog(484519) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • domestic cat(101099259) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • chicken(100858419) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • domestic guinea pig(100734800) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • naked mole-rat(101717375) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • cow(525408) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • sheep(101113618) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

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