NCR3
natural cytotoxicity triggering receptor 3
Synonyms:
1C7, CD337, LY117, MALS, NKp30
Species:
Human NCR3 (259197), Rat Ncr3 (294251), dog NCR3 (607220), sheep NCR3 (101122313), domestic cat NCR3 (101100052), Horse NCR3 (100058447), cow NCR3 (513769)
UniProtKB ID:
Gene ID:
- Human(259197) Summary: The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
- Rat(294251) natural cytotoxicity triggering receptor 3
- dog(607220) natural cytotoxicity triggering receptor 3
- sheep(101122313) natural cytotoxicity triggering receptor 3
- domestic cat(101100052) natural cytotoxicity triggering receptor 3
- Horse(100058447) natural cytotoxicity triggering receptor 3
- cow(513769) natural cytotoxicity triggering receptor 3
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