Skip to Content
Merck

MTHFR

methylenetetrahydrofolate reductase (NAD(P)H)

Synonyms:
Species:
Human MTHFR (4524), Mouse Mthfr (17769), Rat Mthfr (362657), chicken MTHFR (419489), Zebrafish mthfr (567547), naked mole-rat Mthfr (101719335), domestic guinea pig Mthfr (100715703), Domestic Rabbit MTHFR (100352874), sheep MTHFR (101111645), cow MTHFR (497032) ...More
UniProtKB ID:
P42898, B2R7A6, Q5SNW9, Q7Z6M6, Q9UQR2
Gene ID:
  • Human(4524) Summary: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]
  • Mouse(17769) 5,10-methylenetetrahydrofolate reductase
  • Rat(362657) methylenetetrahydrofolate reductase (NAD(P)H)
  • chicken(419489) methylenetetrahydrofolate reductase (NAD(P)H)
  • Zebrafish(567547) methylenetetrahydrofolate reductase (NAD(P)H)
  • naked mole-rat(101719335) methylenetetrahydrofolate reductase (NAD(P)H)
  • domestic guinea pig(100715703) methylenetetrahydrofolate reductase (NAD(P)H)
  • Domestic Rabbit(100352874) methylenetetrahydrofolate reductase (NAD(P)H)
  • sheep(101111645) methylenetetrahydrofolate reductase (NAD(P)H)
  • cow(497032) methylenetetrahydrofolate reductase (NAD(P)H)
  • dog(478230) methylenetetrahydrofolate reductase (NAD(P)H)
  • Horse(100050979) methylenetetrahydrofolate reductase (NAD(P)H)
  • domestic cat(101100576) methylenetetrahydrofolate reductase (NAD(P)H)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
SAB5300417
Monoclonal Anti-MTHFR antibody produced in mouse, clone 5D3, ascites fluid,
Species Reactivity
human, rat
Application
ELISA
immunohistochemistry
western blot
HPA077255
Anti-MTHFR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
HPA076180
Anti-MTHFR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
APREST95373
PrEST Antigen MTHFR, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
APREST95455
PrEST Antigen MTHFR, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human