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Merck

MRPS18C

mitochondrial ribosomal protein S18C

Synonyms:
MRP-S18-1, MRPS18-1
Species:
Human MRPS18C (51023), Mouse Mrps18c (68735), Rat Mrps18c (289469), dog MRPS18C (478458), fruit fly mRpS18C (43609), chicken MRPS18C (770813), Zebrafish mrps18c (569841), naked mole-rat Mrps18c (101721964), domestic guinea pig Mrps18c (100730455), cow MRPS18C (613561) ...More
UniProtKB ID:
Q9Y3D5
Gene ID:
  • Human(51023) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]
  • Mouse(68735) mitochondrial ribosomal protein S18C
  • Rat(289469) mitochondrial ribosomal protein S18C
  • dog(478458) mitochondrial ribosomal protein S18C
  • fruit fly(43609) mitochondrial ribosomal protein S18C
  • chicken(770813) mitochondrial ribosomal protein S18C
  • Zebrafish(569841) mitochondrial ribosomal protein S18C
  • naked mole-rat(101721964) mitochondrial ribosomal protein S18C
  • domestic guinea pig(100730455) mitochondrial ribosomal protein S18C
  • cow(613561) mitochondrial ribosomal protein S18C
  • sheep(101119137) mitochondrial ribosomal protein S18C
  • domestic cat(101084190) mitochondrial ribosomal protein S18C

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