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Merck

MAPK3

mitogen-activated protein kinase 3

Synonyms:
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Species:
Human MAPK3 (5595), Mouse Mapk3 (26417), Rat Mapk3 (50689), Zebrafish mapk3 (399480), domestic cat MAPK3 (101087958), cow MAPK3 (531391), Horse MAPK3 (100066173), dog MAPK3 (479790), sheep MAPK3 (101123008), naked mole-rat Mapk3 (101702687)
UniProtKB ID:
P27361, A8CZ58, B0LPG3, Q8NHX1
Gene ID:
  • Human(5595) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(26417) mitogen-activated protein kinase 3
  • Rat(50689) mitogen activated protein kinase 3
  • Zebrafish(399480) mitogen-activated protein kinase 3
  • domestic cat(101087958) mitogen-activated protein kinase 3
  • cow(531391) mitogen-activated protein kinase 3
  • Horse(100066173) mitogen-activated protein kinase 3
  • dog(479790) mitogen-activated protein kinase 3
  • sheep(101123008) mitogen-activated protein kinase 3
  • naked mole-rat(101702687) mitogen-activated protein kinase 3
  • domestic guinea pig(100725692) mitogen-activated protein kinase 3

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ELISA

Product Number
Description
Species
RAB0349
Phospho-Erk1 (pThr202 / pTyr204 + Erk2 (pTyr185/187) and pan-Erk1 / 2 ELISA Kit, for detection of phospho-erk1 and phospho-erk2 and pan-erk1/2 in human, mouse or rat cell and tissue lysates,
Species
human
RAB0348
Phospho-Erk1 (pThr202 / pTyr204) + Erk2(pTyr185/187) ELISA Kit, for detection of phospho-erk1 and phospho-erk2 in human, mouse or rat cell and tissue lysates,
Species
human
RAB0958
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
Species
human
RAB0350
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Species
mouse, rat, human
RAB0352
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Species
rat, human, mouse

Antibodies

Product Number
Description
Species Reactivity
Application
SAB5300429
Monoclonal Anti-MAPK3 antibody produced in mouse, clone 1E5, ascites fluid,
Species Reactivity
human, monkey, mouse, rat
Application
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
SAB1305560
MONOCLONAL ANTI-ERK1/2 antibody produced in mouse, clone 784CT7.6.3, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
SAB4301578
Anti-phospho-ERK1/2 (pThr202/Tyr204) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
FCMAB100P
Milli-Mark Anti-Phospho-Erk1/2 Antibody (Thr202/Tyr204, Thr185/Tyr187)-PE, clone AW39R, Milli-Mark®, from rabbit,
Species Reactivity
human, mouse, rat
Application
flow cytometry
western blot
SAB1306604
ANTI-BI-PHOSPHO-ERK1/2(T202/Y204) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
14-439-M
MAP Kinase 1/Erk1 Protein, active, 10 µg, Active, recombinant, full-length, human MAP Kinase 1/Erk1 containing an N-terminal GST tag, for use in Kinase Assays.,
Species
human
SRP5282
ERK1, active, GST tagged human, PRECISIO®, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
E7407
ERK1, active, untagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human