MAL
mal, T-cell differentiation protein
Synonyms:
Species:
Human MAL (4118), Mouse Mal (17153), Rat Mal (25263), fruit fly Mal (5656947), fruit fly mal (33045), Zebrafish mal (550381), chicken MAL (416707), dog MAL (403933), domestic cat MAL (101085795), cow MAL (510077) ...More
UniProtKB ID:
Gene ID:
- Human(4118) Summary: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]
- Mouse(17153) myelin and lymphocyte protein, T cell differentiation protein
- Rat(25263) mal, T-cell differentiation protein
- fruit fly(5656947) Malformed
- fruit fly(33045) maroon-like
- Zebrafish(550381) mal, T-cell differentiation protein
- chicken(416707) mal, T-cell differentiation protein
- dog(403933) mal, T-cell differentiation protein
- domestic cat(101085795) mal, T-cell differentiation protein
- cow(510077) mal, T-cell differentiation protein
- domestic guinea pig(100715705) mal, T-cell differentiation protein
- naked mole-rat(101696352) mal, T-cell differentiation protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MAL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Human CD8a (RPA-T8) ColorWheel® Dye-Ready mAb, for use with ColorWheel® Dyes (Required, sold separately),
Species Reactivity
human, nonhuman primates
Application
flow cytometry