LIN28B
lin-28 homolog B (C. elegans)
CSDD2
Human LIN28B (389421), Mouse Lin28b (380669), Rat Lin28b (689054), chicken LIN28B (421786), sheep LIN28B (100861578), cow LIN28B (540646), domestic cat LIN28B (101090940), dog LIN28B (481943), domestic guinea pig Lin28b (100734141)
- Human(389421) Summary: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
- Mouse(380669) lin-28 homolog B (C. elegans)
- Rat(689054) lin-28 homolog B (C. elegans)
- chicken(421786) lin-28 homolog B (C. elegans)
- sheep(100861578) lin-28 homolog B (C. elegans)
- cow(540646) lin-28 homolog B (C. elegans)
- domestic cat(101090940) lin-28 homolog B (C. elegans)
- dog(481943) lin-28 homolog B (C. elegans)
- domestic guinea pig(100734141) lin-28 homolog B (C. elegans)
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siRNA
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Antibodies
Anti-LIN28B (C-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
human
ELISA
western blot
western blot