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Merck

LIN28B

lin-28 homolog B (C. elegans)

Synonyms:
CSDD2
Species:
UniProtKB ID:
Gene ID:
  • Human(389421) Summary: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
  • Mouse(380669) lin-28 homolog B (C. elegans)
  • Rat(689054) lin-28 homolog B (C. elegans)
  • chicken(421786) lin-28 homolog B (C. elegans)
  • sheep(100861578) lin-28 homolog B (C. elegans)
  • cow(540646) lin-28 homolog B (C. elegans)
  • domestic cat(101090940) lin-28 homolog B (C. elegans)
  • dog(481943) lin-28 homolog B (C. elegans)
  • domestic guinea pig(100734141) lin-28 homolog B (C. elegans)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LIN28B (C-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot