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Merck

LGI1

leucine-rich, glioma inactivated 1

Synonyms:
ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099
Species:
UniProtKB ID:
Gene ID:
  • Human(9211) Summary: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. [provided by RefSeq, Jul 2008]
  • Mouse(56839) leucine-rich repeat LGI family, member 1
  • Rat(252892) leucine-rich, glioma inactivated 1
  • sheep(101105294) leucine-rich, glioma inactivated 1
  • dog(477777) leucine-rich, glioma inactivated 1
  • Domestic Rabbit(100344253) leucine-rich, glioma inactivated 1
  • naked mole-rat(101703526) leucine-rich, glioma inactivated 1
  • domestic cat(101088030) leucine-rich, glioma inactivated 1
  • domestic guinea pig(100726518) leucine-rich, glioma inactivated 1
  • cow(617080) leucine-rich, glioma inactivated 1
  • chicken(423802) leucine-rich, glioma inactivated 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LGI1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Lgi1 antibody produced in mouse, clone S283-7, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot