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Merck

KRAS

Kirsten rat sarcoma viral oncogene homolog

Synonyms:
C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Species:
UniProtKB ID:
Gene ID:
  • Human(3845) Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
  • Mouse(16653) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • Rat(24525) Kirsten rat sarcoma viral oncogene
  • Zebrafish(445289) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • sheep(101114005) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • naked mole-rat(101718997) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • chicken(418207) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • dog(403871) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • cow(541140) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • domestic guinea pig(100716262) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KRAS, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast
Application
western blot
Monoclonal Anti-KRAS antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-KRAS antibody produced in mouse, clone 3B10-2F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-Pan-Ras (Ab-3) Mouse mAb (RAS 10), liquid, clone RAS 10, Calbiochem®,
Species Reactivity
human, mouse, rat
Application
Anti-Pan-Ras Antibody, clone RAS 10, clone RAS 10, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KRAS,
Species
human