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Merck

KCNE3

potassium voltage-gated channel, Isk-related family, member 3

Synonyms:
HOKPP, HYPP, MiRP2
Species:
Human KCNE3 (10008), Mouse Kcne3 (57442), Rat Kcne3 (63883), domestic cat KCNE3 (101094205), sheep KCNE3 (101106359), chicken KCNE3 (428105), naked mole-rat Kcne3 (101710164), dog KCNE3 (485197), domestic guinea pig Kcne3 (100719841), cow KCNE3 (527762)
UniProtKB ID:
Q9Y6H6
Gene ID:
  • Human(10008) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]
  • Mouse(57442) potassium voltage-gated channel, Isk-related subfamily, gene 3
  • Rat(63883) potassium voltage-gated channel, Isk-related family, member 3
  • domestic cat(101094205) potassium voltage-gated channel, Isk-related family, member 3
  • sheep(101106359) potassium voltage-gated channel, Isk-related family, member 3
  • chicken(428105) potassium voltage-gated channel, Isk-related family, member 3
  • naked mole-rat(101710164) potassium voltage-gated channel, Isk-related family, member 3
  • dog(485197) potassium voltage-gated channel, Isk-related family, member 3
  • domestic guinea pig(100719841) potassium voltage-gated channel, Isk-related family, member 3
  • cow(527762) potassium voltage-gated channel, Isk-related family, member 3

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