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IRAK3

interleukin-1 receptor-associated kinase 3

Synonyms:
ASRT5, IRAKM
Species:
UniProtKB ID:
Gene ID:
  • Human(11213) Summary: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
  • Mouse(73914) interleukin-1 receptor-associated kinase 3
  • Rat(314870) interleukin-1 receptor-associated kinase 3
  • Zebrafish(567444) interleukin-1 receptor-associated kinase 3
  • dog(481150) interleukin-1 receptor-associated kinase 3
  • domestic cat(101093197) interleukin-1 receptor-associated kinase 3
  • cow(510342) interleukin-1 receptor-associated kinase 3
  • naked mole-rat(101704873) interleukin-1 receptor-associated kinase 3
  • sheep(101115273) interleukin-1 receptor-associated kinase 3
  • domestic guinea pig(100729478) interleukin-1 receptor-associated kinase 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IRAK3 antibody produced in mouse, clone 1A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-IRAK-M antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-IRAK3, (C-terminal) antibody produced in mouse, clone 1F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-IRAK3 antibody produced in mouse, clone 1F1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
ANTI-IRAK3 antibody produced in mouse, clone 1C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

Proteins

Product Number
Description
Species
IRAK3, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human