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Merck

IL6

interleukin 6 (interferon, beta 2)

Synonyms:
BSF2, HGF, HSF, IFNB2, IL-6
Species:
UniProtKB ID:
Gene ID:
  • Human(3569) Summary: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
  • Mouse(16193) interleukin 6
  • Rat(24498) interleukin 6
  • Zebrafish(100885851) interleukin 6 (interferon, beta 2)
  • chicken(395337) interleukin 6 (interferon, beta 2)
  • dog(403985) interleukin 6 (interferon, beta 2)
  • domestic cat(493687) interleukin 6 (interferon, beta 2)
  • Horse(100034196) interleukin 6 (interferon, beta 2)
  • cow(517016) interleukin 6 (interferon, beta 2)
  • cow(280826) interleukin 6 (interferon, beta 2)
  • Goat(100860785) interleukin 6 (interferon, beta 2)
  • sheep(443406) interleukin 6 (interferon, beta 2)
  • Domestic Rabbit(100008733) interleukin 6 (interferon, beta 2)
  • naked mole-rat(101702602) interleukin 6 (interferon, beta 2)

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ELISA

Product Number
Description
Species
Porcine IL-6 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
dog
Canine IL6 / Interleukin-6 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
dog
Mouse IL-6 ELISA Kit, for cell and tissue lysates,
Species
rat
Mouse IL-6 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Rat Interleukin-6 ELISA Kit, for for cell lysate and tissue lysate,
Species
rat

Small Molecule - Antagonist

Product Number
Description
Species
Probucol, analytical standard,
Species
human
4-Hydroxytamoxifen, ≥70% Z isomer (remainder primarily E-isomer),
Species
human, rat
(Z)-4-Hydroxytamoxifen, ≥98% Z isomer,
Species
human, rat
4-Hydroxytamoxifen, analytical standard, (E) and (Z) isomers (50:50),
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL6, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-IL6 antibody produced in mouse, clone 3E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-IL6 antibody produced in mouse, clone 2D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-IL6 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-IL6 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot

Proteins

Product Number
Description
Species
Interleukin-6 human, Animal-component free, recombinant, expressed in E. coli, suitable for cell culture,
Species
human
IL-6 from rat, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
Species
rat
Interleukin-6 from mouse, IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, carrier free,
Species
mouse
Interleukin-6 human, IL-6, recombinant, expressed in E. coli, Carrier Free,
Species
human
Interleukin-6 from rat, IL-6, recombinant, expressed in E. coli, buffered aqueous solution, suitable for cell culture,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il6,
Species
mouse
MISSION® esiRNA, targeting human IL6,
Species
human