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Merck

GLUL

glutamate-ammonia ligase

Synonyms:
GLNS, GS, PIG43, PIG59
Species:
UniProtKB ID:
Gene ID:
  • Human(2752) Summary: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(14645) glutamate-ammonia ligase (glutamine synthetase)
  • Rat(24957) glutamate-ammonia ligase
  • domestic guinea pig(100715062) glutamate-ammonia ligase
  • chicken(396489) glutamate-ammonia ligase
  • Horse(100054716) glutamate-ammonia ligase
  • domestic cat(101093325) glutamate-ammonia ligase
  • dog(403443) glutamate-ammonia ligase
  • cow(281199) glutamate-ammonia ligase

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GLUL antibody produced in mouse, clone 2B12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-Glutamine Synthetase Antibody, clone GS-6, clone GS-6, Chemicon®, from mouse,
Species Reactivity
human, mouse, rat, sheep
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-GLUL antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2999, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-GLUL antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3013, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-Glutamine Synthetase antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
rat
Application
immunohistochemistry
microarray

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
DL-threo-β-Hydroxyaspartic acid, ,
Species
mouse, human
L-2-Aminoadipic acid, ≥98% (TLC),
Species
rat, human