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GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

Synonyms:

GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2

Species:

Human GABBR1 (2550), Mouse Gabbr1 (54393), Rat Gabbr1 (81657), domestic guinea pig Gabbr1 (100170763), naked mole-rat Gabbr1 (101719480), sheep GABBR1 (101110007), Domestic Rabbit GABBR1 (100353026), domestic cat GABBR1 (101099637), dog GABBR1 (488340), cow GABBR1 (513785)

UniProtKB ID:

Q9UBS5, B0UXY7, O95375, O95468, O95975, O96022, Q5STL4, Q5SUJ8

Gene ID:

Human(2550) Summary: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)]
Mouse(54393) gamma-aminobutyric acid (GABA) B receptor, 1
Rat(81657) gamma-aminobutyric acid (GABA) B receptor 1
domestic guinea pig(100170763) gamma-aminobutyric acid (GABA) B receptor, 1
naked mole-rat(101719480) gamma-aminobutyric acid (GABA) B receptor, 1
sheep(101110007) gamma-aminobutyric acid (GABA) B receptor, 1
Domestic Rabbit(100353026) gamma-aminobutyric acid (GABA) B receptor, 1
domestic cat(101099637) gamma-aminobutyric acid (GABA) B receptor, 1
dog(488340) gamma-aminobutyric acid (GABA) B receptor, 1
cow(513785) gamma-aminobutyric acid (GABA) B receptor, 1

Products (21)
Peer Reviewed Papers (44)

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Small Molecule - Agonist

Product Number

Description

Species

Baclofen, Pharmaceutical Secondary Standard; Certified Reference Material,

Species

human

Baclofen, British Pharmacopoeia (BP) Reference Standard,

Species

human

Baclofen, United States Pharmacopeia (USP) Reference Standard,

Species

human

Baclofen, European Pharmacopoeia (EP) Reference Standard,

Species

human

G013

R(+)-Baclofen hydrochloride, solid,

Species

human, mouse, rat

Small Molecule - Allosteric Modulator

Product Number

Description

Species

CGP-13501, ≥98% (HPLC), solid,

Species

human

Small Molecule - Antagonist

Product Number

Description

Species

3-Aminopropylphosphonic acid, 98%,

Species

rat

2-Hydroxysaclofen, ≥98% (TLC), solid,

Species

human

P118

Phaclofen, solid,

Species

human

(±)-Baclofen, ≥98% (HPLC), solid,

Species

human, rat

S166

Saclofen, solid,

Species

mouse, human, rat

Antibodies

Product Number

Description

Species Reactivity

Application

Anti-GABBR1 antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, mouse, rat

Application

ELISA
immunofluorescence
western blot

Anti-GABA-B Receptor antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, mouse, rat

Application

ELISA
immunohistochemistry
western blot

Anti-GABA B Receptor R1 Antibody, serum, from guinea pig,

Species Reactivity

human, mouse, rat

Application

immunohistochemistry
western blot

Anti-GABA B Receptor R1 Antibody, Chemicon^®, from rabbit,

Species Reactivity

rat, spider

Application

western blot

Small Molecule - Inhibitor

Product Number

Description

Species

N142

NO-711 hydrochloride, ≥98% (HPLC),

Species

human

G007

Guvacine hydrochloride, ≥97% (NMR), solid,

Species

human

(±)-Vigabatrin, ,

Species

human