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Merck

FBLIM1

filamin binding LIM protein 1

Synonyms:
CAL, FBLP-1, FBLP1
Species:
UniProtKB ID:
Gene ID:
  • Human(54751) Summary: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(74202) filamin binding LIM protein 1
  • Rat(362650) filamin binding LIM protein 1
  • sheep(101109631) filamin binding LIM protein 1
  • cow(767833) filamin binding LIM protein 1
  • domestic cat(101082251) filamin binding LIM protein 1
  • naked mole-rat(101709740) filamin binding LIM protein 1
  • chicken(419458) filamin binding LIM protein 1
  • dog(608618) filamin binding LIM protein 1
  • domestic guinea pig(100731846) filamin binding LIM protein 1

Custom & Knockdown Gene Products