ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonyms:
HER4, p180erbB4
Species:
Human ERBB4 (2066), Mouse Erbb4 (13869), Rat Erbb4 (59323), naked mole-rat Erbb4 (101725806), domestic guinea pig Erbb4 (100724678), Domestic Rabbit ERBB4 (100009328), sheep ERBB4 (101103044), cow ERBB4 (522419), Horse ERBB4 (100050182), domestic cat ERBB4 (101100073) ...More
UniProtKB ID:
Gene ID:
- Human(2066) Summary: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
- Mouse(13869) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- Rat(59323) v-erb-b2 avian erythroblastic leukemia viral oncogene 4
- naked mole-rat(101725806) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- domestic guinea pig(100724678) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- Domestic Rabbit(100009328) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- sheep(101103044) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- cow(522419) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
- Horse(100050182) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- domestic cat(101100073) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- dog(488508) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- chicken(395671) v-erb-a erythroblastic leukemia viral oncogene homolog 4
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-erbB4 Antibody, clone HFR1/2G4, clone HFR1/2G4, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-c-erbB-4 antibody, Mouse monoclonal, clone HER4-36, purified from hybridoma cell culture,
Species Reactivity
human
Application
immunoprecipitation (IP)
microarray
microarray