E2F5
E2F transcription factor 5, p130-binding
Synonyms:
E2F-5
Species:
Human E2F5 (1875), Mouse E2f5 (13559), Rat E2f5 (116651), domestic cat E2F5 (101096875), domestic guinea pig E2f5 (100718912), naked mole-rat E2f5 (101701212), dog E2F5 (611103), cow E2F5 (539427), sheep E2F5 (101114117), chicken E2F5 (420206)
UniProtKB ID:
Gene ID:
- Human(1875) Summary: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(13559) E2F transcription factor 5
- Rat(116651) E2F transcription factor 5
- domestic cat(101096875) E2F transcription factor 5, p130-binding
- domestic guinea pig(100718912) E2F transcription factor 5, p130-binding
- naked mole-rat(101701212) E2F transcription factor 5, p130-binding
- dog(611103) E2F transcription factor 5, p130-binding
- cow(539427) E2F transcription factor 5, p130-binding
- sheep(101114117) E2F transcription factor 5, p130-binding
- chicken(420206) E2F transcription factor 5, p130-binding
- Zebrafish(402908) E2F transcription factor 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-E2F5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-E2F5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Proteins
Product Number
Description
Species
PrEST Antigen E2F5, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human