DNMT1
DNA (cytosine-5-)-methyltransferase 1
Synonyms:
ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT
Species:
Human DNMT1 (1786), Mouse Dnmt1 (13433), Rat Dnmt1 (84350), Goat DNMT1 (100861294), Zebrafish dnmt1 (30430), domestic cat DNMT1 (101093502), chicken DNMT1 (396011), dog DNMT1 (476715), sheep DNMT1 (443549), naked mole-rat Dnmt1 (101712352) ...More
UniProtKB ID:
Gene ID:
- Human(1786) Summary: DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(13433) DNA methyltransferase (cytosine-5) 1
- Rat(84350) DNA (cytosine-5-)-methyltransferase 1
- Goat(100861294) DNA (cytosine-5-)-methyltransferase 1
- Zebrafish(30430) DNA (cytosine-5-)-methyltransferase 1
- domestic cat(101093502) DNA (cytosine-5-)-methyltransferase 1
- chicken(396011) DNA (cytosine-5-)-methyltransferase 1
- dog(476715) DNA (cytosine-5-)-methyltransferase 1
- sheep(443549) DNA (cytosine-5-)-methyltransferase 1
- naked mole-rat(101712352) DNA (cytosine-5-)-methyltransferase 1
- cow(281119) DNA (cytosine-5-)-methyltransferase 1
- domestic guinea pig(100717406) DNA (cytosine-5-)-methyltransferase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DNMT1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
microarray
western blot
western blot
Anti-DNMT1 Antibody, clone 1L14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Phospho-Dnmt1(Ser714) Antibody, from rabbit,
Species Reactivity
human
Application
ELISA
dot blot
western blot
dot blot
western blot
Rabbit anti-DNMT1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
western blot
Anti-DNMT1 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
microarray
western blot
microarray
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
5-Azacytidine, Hybri-Max™, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Species
human
Proteins
Product Number
Description
Species
DNMT1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
Species
human