DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
Synonyms:
MPHOSPH11, MPP11, ZRF1, ZUO1
Species:
Human DNAJC2 (27000), Mouse Dnajc2 (22791), Rat Dnajc2 (116456), naked mole-rat Dnajc2 (101722375), domestic guinea pig Dnajc2 (100723921), Domestic Rabbit DNAJC2 (100341166), cow DNAJC2 (507897), sheep DNAJC2 (101119299), domestic cat DNAJC2 (101086464), dog DNAJC2 (483275) ...More
UniProtKB ID:
Gene ID:
- Human(27000) Summary: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(22791) DnaJ (Hsp40) homolog, subfamily C, member 2
- Rat(116456) DnaJ (Hsp40) homolog, subfamily C, member 2
- naked mole-rat(101722375) DnaJ (Hsp40) homolog, subfamily C, member 2
- domestic guinea pig(100723921) DnaJ (Hsp40) homolog, subfamily C, member 2
- Domestic Rabbit(100341166) DnaJ (Hsp40) homolog, subfamily C, member 2
- cow(507897) DnaJ (Hsp40) homolog, subfamily C, member 2
- sheep(101119299) DnaJ (Hsp40) homolog, subfamily C, member 2
- domestic cat(101086464) DnaJ (Hsp40) homolog, subfamily C, member 2
- dog(483275) DnaJ (Hsp40) homolog, subfamily C, member 2
- Zebrafish(403080) DnaJ (Hsp40) homolog, subfamily C, member 2
- chicken(417717) DnaJ (Hsp40) homolog, subfamily C, member 2
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