DMGDH
dimethylglycine dehydrogenase
Synonyms:
DMGDHD, ME2GLYDH
Species:
Human DMGDH (29958), Mouse Dmgdh (74129), Rat Dmgdh (245961), Horse DMGDH (100073267), dog DMGDH (488935), chicken DMGDH (416370), Zebrafish dmgdh (100141496), cow DMGDH (504453), domestic cat DMGDH (101089168), Domestic Rabbit DMGDH (100340207) ...More
UniProtKB ID:
Gene ID:
- Human(29958) Summary: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. [provided by RefSeq, Jul 2008]
- Mouse(74129) dimethylglycine dehydrogenase precursor
- Rat(245961) dimethylglycine dehydrogenase
- Horse(100073267) dimethylglycine dehydrogenase
- dog(488935) dimethylglycine dehydrogenase
- chicken(416370) dimethylglycine dehydrogenase
- Zebrafish(100141496) dimethylglycine dehydrogenase
- cow(504453) dimethylglycine dehydrogenase
- domestic cat(101089168) dimethylglycine dehydrogenase
- Domestic Rabbit(100340207) dimethylglycine dehydrogenase
- sheep(101113594) dimethylglycine dehydrogenase
- naked mole-rat(101722315) dimethylglycine dehydrogenase
- domestic guinea pig(100724353) dimethylglycine dehydrogenase
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