CLDN12
claudin 12
Synonyms:
Species:
Human CLDN12 (9069), Mouse Cldn12 (64945), Rat Cldn12 (500000), Horse CLDN12 (100060361), cow CLDN12 (538709), dog CLDN12 (608397), naked mole-rat Cldn12 (101698571), Zebrafish cldn12 (81593), domestic guinea pig Cldn12 (100730214), domestic cat CLDN12 (101081208) ...More
UniProtKB ID:
Gene ID:
- Human(9069) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011]
- Mouse(64945) claudin 12
- Rat(500000) claudin 12
- Horse(100060361) claudin 12
- cow(538709) claudin 12
- dog(608397) claudin 12
- naked mole-rat(101698571) claudin 12
- Zebrafish(81593) claudin 12
- domestic guinea pig(100730214) claudin 12
- domestic cat(101081208) claudin 12
- sheep(101108741) claudin 12
- chicken(771872) claudin 12
- Domestic Rabbit(100328633) claudin 12
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CLDN12 antibody produced in mouse, clone 2D8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA