CLDN11
claudin 11
Synonyms:
OSP, OTM
Species:
Human CLDN11 (5010), Mouse Cldn11 (18417), Rat Cldn11 (84588), chicken CLDN11 (424990), domestic cat CLDN11 (101086744), dog CLDN11 (488160), sheep CLDN11 (101113649), cow CLDN11 (508268), naked mole-rat Cldn11 (101725821), domestic guinea pig Cldn11 (100732534)
UniProtKB ID:
Gene ID:
- Human(5010) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Aug 2010]
- Mouse(18417) claudin 11
- Rat(84588) claudin 11
- chicken(424990) claudin 11
- domestic cat(101086744) claudin 11
- dog(488160) claudin 11
- sheep(101113649) claudin 11
- cow(508268) claudin 11
- naked mole-rat(101725821) claudin 11
- domestic guinea pig(100732534) claudin 11
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CLDN11 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, rabbit
Application
immunohistochemistry
western blot
western blot
Anti-CLDN11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence