CKAP5
cytoskeleton associated protein 5
Synonyms:
CHTOG, MSPS, TOG, TOGp, ch-TOG
Species:
Human CKAP5 (9793), Mouse Ckap5 (75786), Rat Ckap5 (311191), domestic cat CKAP5 (101090894), sheep CKAP5 (101115651), dog CKAP5 (475986), cow CKAP5 (533980), Domestic Rabbit CKAP5 (100351133), chicken CKAP5 (423190), domestic guinea pig Ckap5 (100722796) ...More
UniProtKB ID:
Gene ID:
- Human(9793) Summary: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Mouse(75786) cytoskeleton associated protein 5
- Rat(311191) cytoskeleton associated protein 5
- domestic cat(101090894) cytoskeleton associated protein 5
- sheep(101115651) cytoskeleton associated protein 5
- dog(475986) cytoskeleton associated protein 5
- cow(533980) cytoskeleton associated protein 5
- Domestic Rabbit(100351133) cytoskeleton associated protein 5
- chicken(423190) cytoskeleton associated protein 5
- domestic guinea pig(100722796) cytoskeleton associated protein 5
- Zebrafish(492614) cytoskeleton associated protein 5
- naked mole-rat(101719740) cytoskeleton associated protein 5
- Horse(100050886) cytoskeleton associated protein 5
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