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Merck

ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

Synonyms:
ATP6G3, Vma10
Species:
Human ATP6V1G3 (127124), Mouse Atp6v1g3 (338375), Rat Atp6v1g3 (289407), domestic cat ATP6V1G3 (101093576), cow ATP6V1G3 (613925), dog ATP6V1G3 (490256), chicken ATP6V1G3 (424349), naked mole-rat Atp6v1g3 (101710875), sheep ATP6V1G3 (101102659), domestic guinea pig Atp6v1g3 (100712761)
UniProtKB ID:
Q96LB4, Q495K2, Q495K4, Q5T9L6
Gene ID:
  • Human(127124) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(338375) ATPase, H+ transporting, lysosomal V1 subunit G3
  • Rat(289407) ATPase, H+ transporting, lysosomal V1 subunit G3
  • domestic cat(101093576) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
  • cow(613925) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
  • dog(490256) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
  • chicken(424349) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
  • naked mole-rat(101710875) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
  • sheep(101102659) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
  • domestic guinea pig(100712761) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1408295
Anti-ATP6V1G3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot