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Merck

ARHGAP22

Rho GTPase activating protein 22

Synonyms:
RhoGAP2, RhoGap22
Species:
Human ARHGAP22 (58504), Mouse Arhgap22 (239027), Rat Arhgap22 (306279), dog ARHGAP22 (100685787), domestic cat ARHGAP22 (101095047), sheep ARHGAP22 (101116628), chicken ARHGAP22 (423779), cow ARHGAP22 (509022), Horse ARHGAP22 (100063193), naked mole-rat Arhgap22 (101714898) ...More
UniProtKB ID:
Q7Z5H3, A0AVP7, A5YM75, B9EGA0, O00152, Q6ZSB0
Gene ID:
  • Human(58504) Summary: This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(239027) Rho GTPase activating protein 22
  • Rat(306279) Rho GTPase activating protein 22
  • dog(100685787) Rho GTPase activating protein 22
  • domestic cat(101095047) Rho GTPase activating protein 22
  • sheep(101116628) Rho GTPase activating protein 22
  • chicken(423779) Rho GTPase activating protein 22
  • cow(509022) Rho GTPase activating protein 22
  • Horse(100063193) Rho GTPase activating protein 22
  • naked mole-rat(101714898) Rho GTPase activating protein 22
  • domestic guinea pig(100720863) Rho GTPase activating protein 22
  • Zebrafish(562503) Rho GTPase activating protein 22

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