ANAPC2
anaphase promoting complex subunit 2
Synonyms:
APC2, RP11-350O14.5
Species:
Human ANAPC2 (29882), Mouse Anapc2 (99152), Rat Anapc2 (296558), sheep ANAPC2 (101108299), domestic guinea pig Anapc2 (100730651), naked mole-rat Anapc2 (101719594), Zebrafish anapc2 (100318335), chicken ANAPC2 (417258), dog ANAPC2 (491236), domestic cat ANAPC2 (101082786) ...More
UniProtKB ID:
Gene ID:
- Human(29882) Summary: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
- Mouse(99152) anaphase promoting complex subunit 2
- Rat(296558) anaphase promoting complex subunit 2
- sheep(101108299) anaphase promoting complex subunit 2
- domestic guinea pig(100730651) anaphase promoting complex subunit 2
- naked mole-rat(101719594) anaphase promoting complex subunit 2
- Zebrafish(100318335) anaphase promoting complex subunit 2
- chicken(417258) anaphase promoting complex subunit 2
- dog(491236) anaphase promoting complex subunit 2
- domestic cat(101082786) anaphase promoting complex subunit 2
- cow(100336564) anaphase promoting complex subunit 2
- cow(100337474) anaphase promoting complex subunit 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ANAPC2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot