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Merck

AES

amino-terminal enhancer of split

Synonyms:
AES-1, AES-2, ESP1, GRG, GRG5, TLE5
Species:
UniProtKB ID:
Gene ID:
  • Human(166) Summary: The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14797) amino-terminal enhancer of split
  • Rat(29466) amino-terminal enhancer of split
  • dog(485064) amino-terminal enhancer of split
  • cow(505375) amino-terminal enhancer of split
  • Zebrafish(393395) amino-terminal enhancer of split
  • domestic guinea pig(101788509) amino-terminal enhancer of split
  • naked mole-rat(101722861) amino-terminal enhancer of split
  • chicken(100858542) amino-terminal enhancer of split
  • domestic cat(101083243) amino-terminal enhancer of split
  • sheep(101119474) amino-terminal enhancer of split

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