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Merck

ADORA1

adenosine A1 receptor

Synonyms:
RDC7
Species:
UniProtKB ID:
Gene ID:
  • Human(134) Summary: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11539) adenosine A1 receptor
  • Rat(29290) adenosine A1 receptor
  • chicken(374212) adenosine A1 receptor
  • sheep(101109816) adenosine A1 receptor
  • cow(282133) adenosine A1 receptor
  • domestic guinea pig(100135472) adenosine A1 receptor
  • naked mole-rat(101704638) adenosine A1 receptor
  • Zebrafish(100150997) adenosine A1 receptor
  • dog(403961) adenosine A1 receptor
  • domestic cat(101100536) adenosine A1 receptor

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Small Molecule - Agonist

Product Number
Description
Species
(−)-N6-(2-Phenylisopropyl)adenosine, solid,
Species
human
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Species
human
AB-MECA, solid,
Species
human, rat
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Adenosine, ,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
T62, ≥98% (HPLC), crystalline,
Species
human
Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate, 97%,
Species
human
Tubercidin, from Streptomyces tubercidicus, ~95%,
Species
rat
8-Cyclopentyl-1,3-dimethylxanthine, ≥98% (HPLC), powder,
Species
human
Adenosine amine congener hydrate, solid, ≥98% (HPLC),
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-A1 Adenosine Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Product Number
Description
Species
Nitrendipine, >95%, powder,
Species
human, rat
Caffeine, Sigma Reference Standard, vial of 250 mg,
Species
mouse, human, rat
Caffeine, BioXtra,
Species
mouse, human, rat
Nimodipine, ,
Species
human, rat
Nifedipine, ≥98% (HPLC), powder,
Species
rat, mouse, human

Small Molecule - Inhibitor

Product Number
Description
Species
8-(3-Chlorostyryl)caffeine, ≥98% (HPLC), solid,
Species
human, rat, mouse
EHNA hydrochloride, ≥98% (HPLC),
Species
human
Dilazep dihydrochloride, powder,
Species
human
Galangin, autophagy inducing flavonoid,
Species
human, rat
Flavanone, 98%,
Species
human, rat, mouse

Small Molecule - Ligand

Product Number
Description
Species
2-Chloro-2′-deoxyadenosine, antileukemic,
Species
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Species
rat, human
IB-MECA, solid, ≥98% (HPLC),
Species
human, rat
Chloro-IB-MECA, solid, ≥98% (HPLC),
Species
human, rat
Adenosine, ≥99%,
Species
human, rat