ADAMTSL2
ADAMTS-like 2
Synonyms:
GPHYSD1
Species:
Human ADAMTSL2 (9719), Mouse Adamtsl2 (77794), Rat Adamtsl2 (311827), Zebrafish adamtsl2 (100537087), domestic guinea pig Adamtsl2 (100727597), naked mole-rat Adamtsl2 (101716605), cow ADAMTSL2 (526780), sheep ADAMTSL2 (101111183), dog ADAMTSL2 (491276), Horse ADAMTSL2 (100066494) ...More
UniProtKB ID:
Gene ID:
- Human(9719) Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
- Mouse(77794) ADAMTS-like 2
- Rat(311827) ADAMTS-like 2
- Zebrafish(100537087) ADAMTS-like 2
- domestic guinea pig(100727597) ADAMTS-like 2
- naked mole-rat(101716605) ADAMTS-like 2
- cow(526780) ADAMTS-like 2
- sheep(101111183) ADAMTS-like 2
- dog(491276) ADAMTS-like 2
- Horse(100066494) ADAMTS-like 2
- domestic cat(101086513) ADAMTS-like 2
- chicken(417147) ADAMTS-like 2
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