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Merck

ADAMTS8

ADAM metallopeptidase with thrombospondin type 1 motif, 8

Synonyms:
ADAM-TS8, METH2
Species:
Human ADAMTS8 (11095), Mouse Adamts8 (30806), Rat Adamts8 (300475), chicken ADAMTS8 (769222), domestic cat ADAMTS8 (101096009), dog ADAMTS8 (100684302), sheep ADAMTS8 (101120031), cow ADAMTS8 (512544), naked mole-rat Adamts8 (101699898), domestic guinea pig Adamts8 (100712934)
UniProtKB ID:
Q9UP79, Q9NZS0
Gene ID:
  • Human(11095) Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]
  • Mouse(30806) a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
  • Rat(300475) ADAM metallopeptidase with thrombospondin type 1 motif, 8
  • chicken(769222) ADAM metallopeptidase with thrombospondin type 1 motif, 8
  • domestic cat(101096009) ADAM metallopeptidase with thrombospondin type 1 motif, 8
  • dog(100684302) ADAM metallopeptidase with thrombospondin type 1 motif, 8
  • sheep(101120031) ADAM metallopeptidase with thrombospondin type 1 motif, 8
  • cow(512544) ADAM metallopeptidase with thrombospondin type 1 motif, 8
  • naked mole-rat(101699898) ADAM metallopeptidase with thrombospondin type 1 motif, 8
  • domestic guinea pig(100712934) ADAM metallopeptidase with thrombospondin type 1 motif, 8

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