ACTN1
actinin, alpha 1
Synonyms:
BDPLT15
Species:
Human ACTN1 (87), Mouse Actn1 (109711), Rat Actn1 (81634), Domestic Rabbit ACTN1 (100341378), Zebrafish actn1 (560400), naked mole-rat Actn1 (101711839), domestic guinea pig Actn1 (100721342), cow ACTN1 (524770), chicken ACTN1 (373918), domestic cat ACTN1 (101097986) ...More
UniProtKB ID:
Gene ID:
- Human(87) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109711) actinin, alpha 1
- Rat(81634) actinin, alpha 1
- Domestic Rabbit(100341378) actinin, alpha 1
- Zebrafish(560400) actinin, alpha 1
- naked mole-rat(101711839) actinin, alpha 1
- domestic guinea pig(100721342) actinin, alpha 1
- cow(524770) actinin, alpha 1
- chicken(373918) actinin, alpha 1
- domestic cat(101097986) actinin, alpha 1
- dog(480369) actinin, alpha 1
- sheep(101122194) actinin, alpha 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-α-Actinin Antibody, clone AT6/172, clone AT6/172, Upstate®, from mouse,
Species Reactivity
human, mouse, rabbit
Application
immunocytochemistry
western blot
western blot
Monoclonal Anti-α-Actinin antibody produced in mouse, clone BM-75.2, ascites fluid,
Species Reactivity
bovine, chicken, human, mouse
Application
immunofluorescence
microarray
western blot
microarray
western blot
Proteins
Product Number
Description
Species
α-Actinin from chicken gizzard, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
Species
mouse, chicken, rat, human