ACMSD
aminocarboxymuconate semialdehyde decarboxylase
Synonyms:
Species:
Human ACMSD (130013), Mouse Acmsd (266645), Rat Acmsd (171385), Zebrafish acmsd (557166), chicken ACMSD (424288), dog ACMSD (476125), domestic cat ACMSD (101090201), naked mole-rat Acmsd (101705072), sheep ACMSD (101107168), domestic guinea pig Acmsd (100735977)
UniProtKB ID:
Gene ID:
- Human(130013) Summary: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004]
- Mouse(266645) amino carboxymuconate semialdehyde decarboxylase
- Rat(171385) aminocarboxymuconate semialdehyde decarboxylase
- Zebrafish(557166) aminocarboxymuconate semialdehyde decarboxylase
- chicken(424288) aminocarboxymuconate semialdehyde decarboxylase
- dog(476125) aminocarboxymuconate semialdehyde decarboxylase
- domestic cat(101090201) aminocarboxymuconate semialdehyde decarboxylase
- naked mole-rat(101705072) aminocarboxymuconate semialdehyde decarboxylase
- sheep(101107168) aminocarboxymuconate semialdehyde decarboxylase
- domestic guinea pig(100735977) aminocarboxymuconate semialdehyde decarboxylase
- cow(515030) aminocarboxymuconate semialdehyde decarboxylase
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