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Merck

ACE2

angiotensin I converting enzyme 2

Synonyms:
ACEH
Species:
UniProtKB ID:
Gene ID:
  • Human(59272) Summary: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
  • Mouse(70008) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • Rat(302668) angiotensin I converting enzyme 2
  • Domestic Rabbit(100327258) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • sheep(101103622) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • cow(509235) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • chicken(418623) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • domestic cat(554349) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • Zebrafish(492331) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • naked mole-rat(101697829) angiotensin I converting enzyme 2
  • dog(480847) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • domestic guinea pig(100302675) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ACE2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4035, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-ACE2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4013, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ACE2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ACE2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ACE2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Angiotensin II, Human, Plays an important role in the regulation of blood pressure.,
Species
human
Angiotensin Converting Enzyme-2, ACE2, Human recombinant, ≥1000000 U/mg, expressed in HEK 293 cells,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC),
Species
mouse, human, rat
Hippuryl-His-Leu acetate salt, ,
Species
mouse, human, rat
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, ,
Species
mouse, human, rat