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N27802

Sigma-Aldrich

4-Nitro-3-(trifluoromethyl)phenol

99% (GC)

Synonym(s):

Lamprecide, TFM

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About This Item

Linear Formula:
O2NC6H3(CF3)OH
CAS Number:
88-30-2
Molecular Weight:
207.11
EC Number:
201-818-2
MDL number:
MFCD00014714
UNSPSC Code:
12352100
PubChem Substance ID:
24897596
NACRES:
NA.22

Assay

99% (GC)

form

powder

bp

135-138 °C/0.01 mmHg (lit.)

mp

76-79 °C (lit.)

SMILES string

Oc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI

1S/C7H4F3NO3/c8-7(9,10)5-3-4(12)1-2-6(5)11(13)14/h1-3,12H

InChI key

ZEFMBAFMCSYJOO-UHFFFAOYSA-N

Gene Information

human ... CA2(760)

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Oana Birceanu et al.
Aquatic toxicology (Amsterdam, Netherlands), 94(4), 265-274 (2009-09-01)
Although the pesticide, 3-trifluoromethyl-4-nitrophenol (TFM), has been extensively used to control invasive sea lamprey (Petromyzon marinus) populations in the Great Lakes, it is surprising that its mechanism(s) of toxicity is unresolved. A better knowledge of the mode of toxicity of
Terrance D Hubert et al.
Journal of agricultural and food chemistry, 53(13), 5342-5346 (2005-06-23)
Rainbow trout (Oncorhyncus mykiss) were exposed to the (14)C-labeled lampricide 3-trifluoromethyl-4-nitrophenol (TFM) (2.1 mg/L) or niclosamide (0.055 mg/L) in an aerated static water bath for 24 h. Fish were sacrificed immediately after exposure. Subsamples of skin-on muscle tissue were analyzed
Oana Birceanu et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 153(3), 342-349 (2010-12-22)
The toxicity of 3-trifluoromethyl-4-nitrophenol (TFM) appears to be due to a mismatch between ATP supply and demand in lamprey, depleting glycogen stores and starving the nervous system of ATP. The cause of this TFM-induced ATP deficit is unclear. One possibility
Hongwei Hu et al.
Sensors (Basel, Switzerland), 18(6) (2018-06-08)
The ultrasonic phased array total focusing method (TFM) has the advantages of full-range dynamic focusing and high imaging resolution, but the problem of long imaging time limits its practically industrial applications. To reduce the imaging calculation demand of TFM, the
Jason R Kennerdell et al.
Nature communications, 9(1), 4188-4188 (2018-10-12)
Aging is a prominent risk factor for neurodegenerative disease. Defining gene expression mechanisms affecting healthy brain aging should lead to insight into genes that modulate susceptibility to disease. To define such mechanisms, we have pursued analysis of miR-34 mutants in
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