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330707

Avanti

SPLASH LIPIDOMIX Mass Spec Standard

Avanti Research - A Croda Brand

Synonym(s):

SPLASH LIPIDOMIX Mass Spec Standard, Single-vial Prepared Lipidomic Analytical Standard for Human plasma lipids

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (330707-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

1 mg/mL (330707-1EA)

technique(s)

mass spectrometry (MS): suitable

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

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General description

Make a splash in your lab and dive right into Lipidomics with our easy to use mixture of deuterium labeled lipids. The SPLASH LIPIDOMIX Mass Spec Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample. This internal standard mixture was developed in collaboration with Kim Ekroos (Zora Biosciences).

Application

SPLASH LIPIDOMIX Mass Spec Standard has been used:
  • as an internal standard for non-alcoholic fatty liver disease (NAFLD) signature analysis from mice and human samples
  • as an internal standard in the quantification of phospholipids from duodenum, liver, and adipose tissue using ultra performance liquid chromatography quadrupole-time of-flight mass spectrometry (UPLC-q-Tof MS)
  • in human cell lines prior to lipid analysis by liquid chromatography-mass spectrometry (LC-MS) analysis

Features and Benefits

  • Save time: pre-mixed internal standards.
  • Save money: 1 vial is sufficient for 100 plasma samples.
  • Exact concentrations provided for quantitative lipidomic analysis.
  • Applicable to multiple MS approaches.
  • Concentration of each lipid class optimized for plasma analysis.

Packaging

2 mL Amber Glass Sealed Ampule (330707-1EA)

Components

The SPLASH LIPIDOMIX Mass Spec Standard is supplied in 1 mL of methanol and contains the following components:

Mixture ComponentTarget Conc. (μg/mL)
  • 15:0-18:1(d7) PC160
  • 15:0-18:1(d7) PE5
  • 15:0-18:1(d7) PS5
  • 15:0-18:1(d7) PG30
  • 15:0-18:1(d7) PI10
  • 15:0-18:1(d7) PA7
  • 18:1(d7) LPC25
  • 18:1(d7) LPE5
  • 18:1(d7) Chol Ester350
  • 18:1(d7) MG2
  • 15:0-18:1(d7) DG10
  • 15:0-18:1(d7)-15:0 TG55
  • 18:1(d9) SM30
  • Cholesterol (d7)100

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

Kit Components Also Available Separately

Product No.
Description
SDS

  • 791637C15:0-18:1-d7-PC, Avanti Research - A Croda Brand 160μg/mLSDS

  • 791638C15:0-18:1-d7-PE, Avanti Research - A Croda Brand 5μg/mLSDS

  • 791639C15:0-18:1-d7-PS, Avanti Research - A Croda Brand 5μg/mLSDS

  • 791640C15:0-18:1-d7-PG, Avanti Research - A Croda Brand 791640C 30μg/mLSDS

  • 791641C15:0-18:1-d7-PI, Avanti Research - A Croda Brand 10μg/mLSDS

  • 791642C15:0-18:1-d7-PA, Avanti Research - A Croda Brand 7μg/mLSDS

  • 791643C18:1-d7 Lyso PC, Avanti Research - A Croda Brand 25μg/mLSDS

  • 791644C18:1-d7 Lyso PE, Avanti Research - A Croda Brand 791644C 5μg/mLSDS

  • 791645C18:1-d7-cholesterol, Avanti Research - A Croda Brand 791645C 350μg/mLSDS

  • 791646C18:1-d7 MG, Avanti Research - A Croda Brand 791646C 2μg/mLSDS

  • 791647C15:0-18:1-d7 DG, Avanti Research - A Croda Brand 791647C 10μg/mLSDS

  • 791648C15:0-18:1-d7-15:0 TG, Avanti Research - A Croda Brand 791648C 55μg/mLSDS

  • 791649C18:1-d9 SM, Avanti Research - A Croda Brand 30μg/mLSDS

  • 700041Pcholesterol-d7, Avanti Research - A Croda Brand 100μg/mLSDS

See All (14)

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


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Diana Széliová et al.
Methods in molecular biology (Clifton, N.J.), 2088, 119-160 (2020-01-02)
Biomass composition is an important input for genome-scale metabolic models and has a big impact on their predictive capabilities. However, researchers often rely on generic data for biomass composition, e.g. collected from similar organisms. This leads to inaccurate predictions, because
Michal Holčapek et al.
Analytical chemistry, 90(7), 4249-4257 (2018-03-16)
The state-of-art in the lipidomic analysis is summarized here to provide the overview of available sample preparation strategies, mass spectrometry (MS)-based methods for the qualitative analysis of lipids, and the quantitative MS approaches for high-throughput clinical workflows. Major challenges in
Bobbie-Jo M Webb-Robertson et al.
Analytical chemistry, 92(2), 1796-1803 (2019-11-20)
Advancements in molecular separations coupled with mass spectrometry have enabled metabolome analyses for clinical cohorts. A population of interest for metabolome profiling is patients with rare disease for which abnormal metabolic signatures may yield clues into the genetic basis, as
Mike Lange et al.
Analytical and bioanalytical chemistry, 412(15), 3573-3584 (2020-04-03)
Lipidomics analysis for large-scale studies aiming at the identification and quantification of natural lipidomes is often performed using LC-MS-based data acquisition. However, the choice of suitable LC-MS method for accurate lipid quantification remains a matter of debate. Here, we performed
Isha H Jain et al.
Cell, 181(3), 716-727 (2020-04-08)
Human cells are able to sense and adapt to variations in oxygen levels. Historically, much research in this field has focused on hypoxia-inducible factor (HIF) signaling and reactive oxygen species (ROS). Here, we perform genome-wide CRISPR growth screens at 21%

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