C39601

Chlorodiphenylphosphine

96%

• Synonym(s): P-Chlorodiphenylphosphine, ClPPh₂, PPh₂Cl, Diphenylphosphinous chloride
• Linear Formula: (C₆H₅)₂PCl
• CAS Number: 1079-66-9
• Molecular Weight: 220.63
• Beilstein: 512032
• EC Number: 214-093-2
• MDL number: MFCD00000529
• UNSPSC Code: 12352128
• PubChem Substance ID: 24892660
• NACRES: NA.22

Properties

• vapor density: 7.8 (vs air)
• Quality Level: 100
• Assay: 96%
• form: liquid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Cross Couplings; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• refractive index: n20/D 1.636 (lit.)
• bp: 320 °C (lit.)
• density: 1.194 g/mL at 25 °C; 1.229 g/mL at 25 °C (lit.)
• functional group: phosphine
• SMILES string: ClP(c1ccccc1)c2ccccc2
• InChI: 1S/C12H10ClP/c13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H
• InChI key: XGRJZXREYAXTGV-UHFFFAOYSA-N

Description

General description

Ph₂PCl is an efficient reagent for cross-coupling reactions and for introducing the Ph₂P group into molecules.

Application

Precursors used in the synthesis of various phosphines.

Used to introduce the diphenylphosphinyl moiety by aryl ortho-lithiation.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H290,H302,H314,H412
• Precautionary Statements: P234 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Supplementary Hazards: EUH014
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): 280.4 °F
• Flash Point(C): 138 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves