Skip to Content
Merck
  • Cp* iridium complexes give catalytic alkane hydroxylation with retention of stereochemistry.

Cp* iridium complexes give catalytic alkane hydroxylation with retention of stereochemistry.

Journal of the American Chemical Society (2010-08-25)
Meng Zhou, Nathan D Schley, Robert H Crabtree
ABSTRACT

A series of Cp*Ir complexes can catalyze C-H oxidation, with ceric ammonium nitrate as the terminal oxidant and water as the source of oxygen. Remarkably the hydroxylation of cis-decalin and 1,4-dimethylcyclohexane proceeds with retention of stereochemistry. With H(2)O(18), cis-decalin oxidation gave (18)O incorporation into the product cis-decalol.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ammonium cerium(IV) nitrate, ≥99.99% trace metals basis
Sigma-Aldrich
Ammonium cerium(IV) nitrate, ≥98% (titration)
Sigma-Aldrich
Ammonium cerium(IV) nitrate, ACS reagent, ≥98.5%
Sigma-Aldrich
Ammonium cerium(IV) nitrate, puriss. p.a., ACS reagent, ≥98.5% (RT)
Sigma-Aldrich
Ammonium cerium(IV) nitrate, JIS special grade, ≥95.0%