765112
Poly(L-lactide)
average Mn 10,000, PDI ≤1.1
Synonym(s):
PLA, PLLA, Polylactide, L-Lactide polymer, PLA, Poly(L-Lactic acid)
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About This Item
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form
solid
optical activity
[α]22/D -150°, c = 0.5% in chloroform
mol wt
average Mn 10,000
degradation timeframe
>3 years
transition temp
Tm 162-167 °C
PDI
≤1.1
storage temp.
2-8°C
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General description
Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.
Application
Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.
Features and Benefits
High initial strength, good strength retention and high amount of crystallinity, as much as 70%, which in turn is responsible for the very slow degradation rate.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Eur. Polymer J., 36(2), 435-442 (2000)
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Macromolecules, 44, 2589-2596 (2011)
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